Studies on the Hemolytic Streptococcus

Studies on Hemolytic Streptococci: II. Streptococcus pyogenes.

Studies on the Hemolytic Streptococcus of Human Origin

1. Four common variants of the hemolytic streptococcus of human origin have been described. These have been designated the F, M, attenuated M, and C variants. 2. The F and M variants only have been isolated from the blood stream in streptococcal infections. Only the M, however, has any primary virulence for the mouse. 3. Both these variants resist phagocytosis in human blood under suitable cond...

Studies on a Non-hemolytic Streptococcus Isolated from the Respiratory Tract of Human Beings

The results of studies on the antigenic structure and immunological specificity of a non-hemolytic streptococcus, designated streptococcus MG, are described. Evidence is presented to show that this microorganism possesses a capsule and that this structure contains a polysaccharide antigen which is responsible for the type specific serological reactions obtained with streptococcus MG.

Studies on the Bacteriophages of Hemolytic Streptococci

The lysis of cell walls of hemolytic streptococci by a phage-associated lysin has been described. A method is presented for preparing the lysin from Group C streptococcal phage lysates. Following lysis almost all of the cell wall carbohydrate is recovered in solution. This material has the serological reactivity, physical-chemical properties, and values for nitrogen, rhamnose, and glucosamine s...

Studies on Heterogeneous Hemolytic Sera

Red corpuscles with nuclei contain heterogeneous sheep antigen when the organs of the same animal possess it. The sera in question contain not only heterogeneous hemolysins but also heterogeneous agglutinins. The hemolytic sera of rabbits immunized with hen red corpuscles are toxic to guinea pigs and kill them, the clinical picture being that of anaphylactic shock. Heterogeneous hemolysins are ...